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UCSF ASPIRE: Assessing the Safety of Pregnancy In the CoRonavirus PandEmic

A nationwide prospective cohort study of pregnant women and their offspring during the COVID-19 pandemic.

This study is being done to help understand the spread of COVID-19 infection among pregnant women and how infection might affect the health and wellbeing of pregnant mothers and their babies.

The Assessing the Safety of Pregnancy in the Coronavirus Pandemic study is a research study run by and affiliated with the University of California, San Francisco, and is not affiliated with any other organization named Aspire in Texas, Georgia, or other locations.

Study overview



Research Topic

Covid-19, Pregnancy




United States (Nationwide)



What is the purpose of this study?

We want to understand how COVID-19 infection affects the health and wellbeing of pregnant mothers and their babies. 

ASPIRE is focused on the first trimester, a critical and vulnerable period when all of a baby’s organ systems form and the placenta - the crucial connection between mom and baby - develops.

Currently, there are no data about the effects of COVID-19 infections in the first trimester. Our study will provide critical information to:

(1)  Guide the care of pregnant women

(2)  Protect the safety of their babies and families

(3)  Help those considering pregnancy in the future understand what it means to be pregnant in this new era

We are recruiting 10,000 women from the start of pregnancy and will track COVID-19 exposures using frequent serology testing. We will collect information during and after the pregnancy to try to determine the effects of COVID 19 for mom and baby.

Who can join?

You may be able to join if...



  • Over age 18
  • You are 4-10 weeks pregnant (gestation)
  • You have not received any dose of a COVID vaccine prior to your first missed period

What will I receive?

Participants are eligible to receive up to $170.

Frequently asked question

Interesting in getting started?

Connect with Us:

Twitter: @study_aspire

Instagram: @study_aspire